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(E) Yes. Heparin-induced thrombocytopenia (HIT) occurs much less commonly with LWMH than with UFH, but it can still occur. A baseline thrombocytopenia (platelets < 100,000) should be viewed as a contraindication to outpatient therapy. Once on therapy, it is recommended that a LMWH be stopped if the platelet count drops below 100,000 mm3.(10, 11, 12, 13, 16) |