ARTHRITIS PAIN
What
Is Arthritis?
The word arthritis
literally means joint inflammation, but is often used to refer
to a group of more than 100 rheumatic diseases that can cause
pain, stiffness, and swelling in the joints. These diseases
may affect not only the joints but also other parts of the body,
including important supporting structures such as muscles, bones,
tendons, and ligaments, as well as some internal organs. This
fact sheet focuses on pain caused by two of the most common
forms of arthritis—osteoarthritis and rheumatoid arthritis.
What
Is Pain?
Pain is the body’s
warning system, alerting you that something is wrong. The International
Association for the Study of Pain defines it as an unpleasant
experience associated with actual or potential tissue damage
to a person’s body. Specialized nervous system cells (neurons)
that transmit pain signals are found throughout the skin and
other body tissues. These cells respond to things such as injury
or tissue damage. For example, when a harmful agent such as
a sharp knife comes in contact with your skin, chemical signals
travel from neurons in the skin through nerves in the spinal
cord to your brain, where they are interpreted as pain.
Most forms of arthritis
are associated with pain that can be divided into two general
categories: acute and chronic. Acute pain is temporary. It can
last a few seconds or longer but wanes as healing occurs. Some
examples of things that cause acute pain include burns, cuts,
and fractures. Chronic pain, such as that seen in people with
osteoarthritis and rheumatoid arthritis, ranges from mild to
severe and can last a lifetime.
How
Many Americans Suffer From Arthritis Pain?
Chronic pain is
a major health problem in the United States and is one of the
most weakening effects of arthritis. More than 40 million Americans
suffer from some form of arthritis, and many have chronic pain
that limits daily activity. Osteoarthritis is by far the most
common form of arthritis, affecting about 16 million Americans,
while rheumatoid arthritis, which affects about 2.1 million
Americans, is the most crippling form of the disease.
What
Causes Arthritis Pain? Why Is It So Variable?
The pain of arthritis
may come from different sources. These may include inflammation
of the synovial membrane (tissue that lines the joints), the
tendons, or the ligaments; muscle strain; and fatigue. A combination
of these factors contributes to the intensity of the pain.
The pain of arthritis
varies greatly from person to person, for reasons that doctors
do not yet understand completely. Factors that contribute to
the pain include swelling within the joint, the amount of heat
or redness present, or damage that has occurred within the joint.
In addition, activities affect pain differently so that some
patients note pain in their joints after first getting out of
bed in the morning whereas others develop pain after prolonged
use of the joint. Each individual has a different threshold
and tolerance for pain, often affected by both physical and
emotional factors. These can include depression, anxiety, and
even hypersensitivity at the affected sites due to inflammation
and tissue injury. This increased sensitivity appears to affect
the amount of pain perceived by the individual.
How
Do Doctors Measure Arthritis Pain?
Pain is a private,
unique experience that cannot be seen. The most common way to
measure pain is for the doctor to ask you, the patient, about
your problems. For example, the doctor may ask you to describe
the level of pain you feel on a scale of 1 to 10. You may use
words like aching, burning, stinging, or throbbing. These words
will give the doctor a clearer picture of the pain you are experiencing.
Since doctors rely
on your description of pain to help guide treatment, you may
want to keep a pain diary to record your pain sensations. On
a daily basis, you can describe the situations that cause or
alter the intensity of your pain, the sensations and severity
of your pain, and your reactions to the pain. For example: “On
Monday night, sharp pains in my knees produced by housework
interfered with my sleep; on Tuesday morning, because of the
pain, I had a hard time getting out bed. However, I coped with
the pain by taking my medication and applying ice to my knees.”
The diary will give the doctor some insight into your pain and
may play a critical role in the management of your disease.
What
Will Happen When You First Visit a Doctor for Your Arthritis
Pain?
The doctor will usually
do the following:
- Take your medical
history and ask questions such as: How long have you had this
problem? How intense is the pain? How often does it occur?
What causes it to get worse? What causes it to get better?
- Review the medications
you are using
- Conduct a physical
examination
- Take blood and/or
urine samples and request necessary laboratory work
- Ask you to get
x rays taken or undergo other imaging procedures such as a
CAT scan (computerized axial tomography) or MRI (magnetic
resonance imaging).
Once the doctor has
done these things and reviewed the results of any tests or procedures,
he or she will discuss the findings with you and design a comprehensive
management approach for the pain caused by your osteoarthritis
or rheumatoid arthritis.
Who
Can Treat Arthritis Pain?
A number of different
specialists may be involved in the care of an arthritis patient—often
a team approach is used. The team may include doctors who treat
people with arthritis (rheumatologists), surgeons (orthopaedists),
and physical and occupational therapists. Their goal is to treat
all aspects of arthritis pain and help you learn to manage your
pain. The physician, other health care professionals, and you,
the patient, all play an active role in the management of arthritis
pain.
How
Is Arthritis Pain Treated?
There is no single
treatment that applies to all people with arthritis, but rather
the doctor will develop a management plan designed to minimize
your specific pain and improve the function of your joints.
A number of treatments can provide short-term pain relief.
Short-Term
Relief
- Medications—Because
people with osteoarthritis have very little inflammation,
pain relievers such as acetaminophen (Tylenol*) may be effective.
Patients with rheumatoid arthritis generally have pain caused
by inflammation and often benefit from aspirin or other nonsteroidal
anti- inflammatory drugs (NSAIDs) such as ibuprofen (Motrin
or Advil).
- Heat and cold—The
decision to use either heat or cold for arthritis pain depends
on the type of arthritis and should be discussed with your
doctor or physical therapist. Moist heat, such as a warm bath
or shower, or dry heat, such as a heating pad, placed on the
painful area of the joint for about 15 minutes may relieve
the pain. An ice pack (or a bag of frozen vegetables) wrapped
in a towel and placed on the sore area for about 15 minutes
may help to reduce swelling and stop the pain. If you have
poor circulation, do not use cold packs.
- Joint Protection—Using
a splint or a brace to allow joints to rest and protect them
from injury can be helpful. Your physician or physical therapist
can make recommendations.
- Transcutaneous
electrical nerve stimulation (TENS)—A small TENS device
that directs mild electric pulses to nerve endings that lie
beneath the skin in the painful area may relieve some arthritis
pain. TENS seems to work by blocking pain messages to the
brain and by modifying pain perception.
- Massage—In
this pain-relief approach, a massage therapist will lightly
stroke and/or knead the painful muscle. This may increase
blood flow and bring warmth to a stressed area. However, arthritis-stressed
joints are very sensitive so the therapist must be very familiar
with the problems of the disease.
- Acupuncture—This
procedure should only be done by a licensed acupuncture therapist.
In acupuncture, thin needles are inserted at specific points
in the body. Scientists think that this stimulates the release
of natural, pain-relieving chemicals produced by the brain
or the nervous system.
Osteoarthritis and
rheumatoid arthritis are chronic diseases that may last a lifetime.
Learning how to manage your pain over the long term is an important
factor in controlling the disease and maintaining a good quality
of life. Following are some sources of long- term pain relief.
Long-Term
Relief
- Medications
Nonsteroidal anti-inflammatory drugs (NSAIDs)—These
are a class of drugs including aspirin and ibuprofen that
are used to reduce pain and inflammation and may be used for
both short-term and long-term relief in people with osteoarthritis
and rheumatoid arthritis.
Disease-modifying anti-rheumatic drugs (DMARDS)—These
are drugs used to treat people with rheumatoid arthritis who
have not responded to NSAIDs. Some of these include methotrexate,
hydroxychloroquine, penicillamine, and gold injections. These
drugs are thought to influence and correct abnormalities of
the immune system responsible for a disease like rheumatoid
arthritis. Treatment with these medications requires careful
monitoring by the physician to avoid side effects.
Corticosteroids—These are hormones that are very effective
in treating arthritis. Corticosteroids can be taken by mouth
or given by injection. Prednisone is the corticosteroid most
often given by mouth to reduce the inflammation of rheumatoid
arthritis. In both rheumatoid arthritis and osteoarthritis,
the doctor also may inject a corticosteroid into the affected
joint to stop pain. Because frequent injections may cause
damage to the cartilage, they should only be done once or
twice a year.
- Weight reduction—Excess
pounds put extra stress on weight-bearing joints such as the
knees or hips. Studies have shown that overweight women who
lost an average of 11 pounds substantially reduced the development
of osteoarthritis in their knees. In addition, if osteoarthritis
has already affected one knee, weight reduction will reduce
the chance of it occurring in the other knee.
- Exercise—Swimming,
walking, low-impact aerobic exercise, and range-of- motion
exercises may reduce joint pain and stiffness. In addition,
stretching exercises are helpful. A physical therapist can
help plan an exercise program that will give you the most
benefit. (The National Arthritis and Musculoskeletal and Skin
Diseases Information Clearinghouse has a separate fact sheet
on arthritis and exercise. See the end of this fact sheet
for contact information.)
- Surgery—In
select patients with arthritis, surgery may be necessary.
The surgeon may perform an operation to remove the synovium
(synovectomy), realign the joint (osteotomy), or in advanced
cases replace the damaged joint with an artificial one. Total
joint replacement has provided not only dramatic relief from
pain but also improvement in motion for many people with arthritis.
What
Alternative Therapies May Relieve Arthritis Pain?
Many people seek
other ways of treating their disease, such as special diets
or supplements. Although these methods may not be harmful in
and of themselves, no research to date shows that they help.
Nonetheless, some alternative or complementary approaches may
help you to cope or reduce some of the stress of living with
a chronic illness. If the doctor feels the approach has value
and will not harm you, it can be incorporated into your treatment
plan. However, it is important not to neglect your regular health
care or treatment of serious symptoms.
How
Can You Cope With Arthritis Pain?
The long-term goal
of pain management is to help you cope with a chronic, often
disabling disease. You may be caught in a cycle of pain, depression,
and stress. To break out of this cycle, you need to be an active
participant with the doctor and other health care professionals
in managing your pain. This may include physical therapy, cognitive-behavioral
therapy, occupational therapy, biofeedback, relaxation techniques
(for example, deep breathing and meditation), and family counseling
therapy.
Another technique
is to substitute distraction for pain. Focus your attention
on things that you enjoy. Imagine a peaceful setting and wonderful
physical sensations. Thinking about something that is enjoyable
can help you relax and become less stressed. Find something
that will make you laugh—a cartoon, a funny movie, or even a
new joke. Try to put some joy back into your life. Even a small
change in your mental image may break the pain cycle and provide
relief.
The Multipurpose
Arthritis and Musculoskeletal Diseases Center at Stanford University,
supported by the National Institute of Arthritis and Musculoskeletal
and Skin Diseases (NIAMS), has developed an Arthritis Self-Help
Course that teaches people with arthritis how to take a more
active part in their arthritis care. The Arthritis Self-Help
Course is taught by the Arthritis Foundation and consists of
a 12- to 15-hour program that includes lectures on osteoarthritis
and rheumatoid arthritis, exercise, pain management, nutrition,
medication, doctor-patient relationships, and nontraditional
treatment.
You may want to contact
some of the organizations listed at the end of this fact sheet
for additional information on the Arthritis Self-Help Course
and on coping with pain, as well as for information on support
groups in your area.
Things
You Can Do To Manage Arthritis Pain
- Eat a
healthy diet
- Get 8
to 10 hours of sleep at night.
- Keep a
daily diary of pain and mood changes to share with
your physician.
- Choose
a caring physician.
- Join a
support group
- Stay informed
about new research on managing arthritis pain.
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What
Research Is Being Conducted On Arthritis Pain?
NIAMS,
part of the National Institutes of Health, is sponsoring research
that will increase understanding of the specific ways to diagnose,
treat, and possibly prevent arthritis pain.
Recent
NIAMS studies show that levels of several neuropeptides (compounds
produced by cells of the nervous system), such as substance
P, are increased in arthritic joints. Substance P is involved
in the transmission of pain signals via the nervous system.
At the University of Missouri-Kansas City, researchers are
studying effects of substance P in the spines of animals with
chronic arthritis. Findings from this study may be used to
develop specific drugs for chronic pain such as that associated
with arthritis.
NIAMS
studies are also looking at other aspects of pain. At the
Specialized Center of Research in Osteoarthritis at Rush-Presbyterian-St
Luke’s Medical Center in Chicago, Illinois, researchers are
studying the human knee and analyzing how injury in one joint
may affect other joints. In addition, they are analyzing the
effect of pain and analgesics on gait (walking) and comparing
pain and gait before and after surgical treatment of knee
osteoarthritis.
At
the University of Maryland Pain Center in Baltimore, NIAMS
researchers are evaluating the use of acupuncture on patients
with osteoarthritis of the knee. Preliminary findings suggest
that traditional Chinese acupuncture is both safe and effective
as an additional therapy for osteoarthritis, and it significantly
reduces pain and improves physical function.
At
Duke University in Durham, North Carolina, NIAMS researchers
have developed cognitive-behavioral therapy (CBT) involving
both patients and their spouses. The goal of CBT for arthritis
pain is to help patients cope more effectively with the long-term
demands of a chronic and potentially disabling disease. Researchers
are studying whether aerobic fitness, coping abilities, and
spousal responses to pain behaviors diminish the patient’s
pain and disability.
NIAMS-supported
research on arthritis pain also includes projects in the Institute’s
Multipurpose Arthritis and Musculoskeletal Diseases Centers.
At the University of California in San Francisco, researchers
are studying stress factors, including pain, that are associated
with rheumatoid arthritis. Findings from this study will be
used to develop patient education programs that will improve
a person’s ability to deal with rheumatoid arthritis and enhance
their quality of life. At the Indiana University School of
Medicine in Indianapolis, health care professionals are monitoring
joint pain in patients with osteoarthritis and documenting
this information. The goal of the project is to improve doctor-patient
communication about pain management and increase patient satisfaction.
Where
Can You Find More Information on Arthritis Pain?
- Arthritis Foundation
1330 West Peachtree Street
Atlanta, GA 30309
404/872-7100 or call your local chapter, (listed in the telephone
directory)
800/283-7800
World Wide Web address: http://www.arthritis.org
This is the major voluntary organization devoted to arthritis.
The Foundation publishes a free brochure, Coping With Pain,
and a monthly magazine for members that provides up- to-date
information on all forms of arthritis. The Foundation also
can provide addresses and phone numbers for their local chapters
and physician and clinic referrals.
- American Chronic
Pain Association
P.O. Box 850
Rocklin, CA 95677
916/632-0922
The Association provides information on positive ways to deal
with chronic pain, and can provide guidelines on selecting
a pain management center.
- American Pain
Society
4700 West Lake Avenue
Glenview, IL 60025-1485
847/375-4715
The Society provides general information to the public and
maintains a directory of resources, including referrals to
pain centers.
- National Chronic
Pain Outreach Association, Inc.
P.O. Box 274
Millboro, VA 24460
540/997-5004
The Association operates an information clearinghouse offering
publications and cassette tapes for people with pain. They
also publish a newsletter that includes information on pain
management techniques, coping strategies, book reviews, and
support groups.
- NAMSIC
National Institutes of Health
1 AMS Circle
Bethesda, MD 20892-3675
301/495-4484
Fax: 301/587-4352
TTY: 301/565-2966
World Wide Web address: http://www.nih.gov/niams/
NIAMS Fast Facts: 301/881-2731 (information 24 hours
a day by fax)
* Brand names included
in this fact sheet are provided as examples only and their inclusion
does not mean that these products are endorsed by the National
Institutes of Health or any other Government agency. Also, if
a particular brand name is not mentioned, this does not mean or
imply that the product is unsatisfactory.
Acknowledgments
The NIAMS gratefully
acknowledges the assistance of John H. Klippel, M.D., Clinical
Director, National Institute of Arthritis and Musculoskeletal
and Skin Diseases; Brian M. Berman, M.D., Director of the Complementary
Medicine Program, University of Maryland, School of Medicine;
and Laurence A. Bradley, Ph.D., Professor of Medicine/Rheumatology,
University of Alabama at Birmingham.
The National Arthritis
and Musculoskeletal and Skin Diseases Information Clearinghouse
(NAMSIC) is a public service sponsored by the NIAMS that provides
health information and information sources, including additional
information on arthritis. The NIAMS, a part of the National
Institutes of Health (NIH), leads the Federal medical research
effort in arthritis and musculoskeletal and skin diseases. The
NIAMS sponsors research and research training throughout the
United States as well as on the NIH campus in Bethesda, Maryland,
and disseminates health and research information.
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