Kawasaki Disease
(mucocutaneous lymph node syndrome)
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Affecting children under the
age of 5, diagnostic criteria include at least 5 days of fever, conjunctival
injection without exudate, red-fissured lips, strawberry tongue, erythematous
rash, redness and/or edema of palms and soles, and cervical adenopathy.
Although generally benign and
self-limited, it is associated with coronary artery aneurisms in about
25% of affected children. Early treatment with high-dose IV gamma-globulin
and oral aspirin have been shown to reduce the incidence of aneurisms.